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00000EF0: 24 B2 22 4E 22 A7 31 30 30 30 00 03 13 B6 03 89 |$."N".1000......|
00000F00: 39 33 30 00 2D 13 E8 03 99 22 93 D0 4C 4F 54 20 |930.-...."..LOT |
00000F10: 47 52 41 50 48 53 20 4F 46 20 54 48 45 20 44 41 |GRAPHS OF THE DA|
00000F20: 54 41 20 59 4F 55 20 48 41 56 45 20 22 00 50 13 |TA YOU HAVE ".P.|
00000F30: F2 03 99 22 4F 42 54 41 49 4E 45 44 20 49 4E 20 |..."OBTAINED IN |
00000F40: 54 48 49 53 20 53 49 4D 55 4C 41 54 49 4F 4E 2E |THIS SIMULATION.|
00000F50: 00 80 13 FC 03 99 22 11 11 11 C9 4E 20 57 48 41 |......"....N WHA|
00000F60: 54 20 57 41 59 20 41 52 45 20 43 4F 4E 53 45 43 |T WAY ARE CONSEC|
00000F70: 55 54 49 56 45 20 52 45 41 43 54 49 4F 4E 53 22 |UTIVE REACTIONS"|
00000F80: 00 B6 13 06 04 99 22 52 45 4C 45 56 41 4E 54 20 |......"RELEVANT |
00000F90: 49 4E 20 4F 55 52 20 4C 49 56 45 53 20 41 4E 44 |IN OUR LIVES AND|
00000FA0: 20 57 48 59 20 49 53 20 54 48 49 53 20 20 20 53 | WHY IS THIS S|
00000FB0: 4F 3F 11 11 11 22 00 00 14 10 04 8F 2D 41 4E 53 |O?..."......-ANS|
00000FC0: 57 45 52 2D 54 48 45 20 41 42 53 4F 52 50 54 49 |WER-THE ABSORPTI|
00000FD0: 4F 4E 20 4F 46 20 44 52 55 47 53 2F 41 4C 43 4F |ON OF DRUGS/ALCO|
00000FE0: 48 4F 4C 20 49 4E 54 4F 20 4F 55 52 20 42 4C 4F |HOL INTO OUR BLO|
00000FF0: 4F 44 53 54 52 45 41 4D 2C 41 4E 44 20 54 48 45 |ODSTREAM,AND THE|
00001000: 00 44 14 1A 04 8F 2D 41 4D 4F 55 4E 54 20 4F 46 |.D....-AMOUNT OF|
00001010: 20 54 49 4D 45 20 54 48 45 59 20 41 52 45 20 41 | TIME THEY ARE A|
00001020: 54 20 41 43 54 49 56 45 20 43 4F 4E 43 45 4E 54 |T ACTIVE CONCENT|
00001030: 52 41 54 49 4F 4E 53 20 42 45 46 4F 52 45 20 42 |RATIONS BEFORE B|
00001040: 45 49 4E 47 00 76 14 24 04 8F 2D 44 49 53 43 48 |EING.v.$..-DISCH|
00001050: 41 52 47 45 44 20 46 52 4F 4D 20 4F 55 52 20 42 |ARGED FROM OUR B|
00001060: 4F 44 49 45 53 20 56 49 41 20 54 48 45 20 4B 49 |ODIES VIA THE KI|
00001070: 44 4E 45 59 53 2E 00 B5 14 2E 04 8F 2D 4B 31 20 |DNEYS.......-K1 |
00001080: 43 4F 4E 54 52 4F 4C 53 20 52 41 54 45 20 46 52 |CONTROLS RATE FR|
00001090: 4F 4D 20 44 49 47 45 53 54 49 56 45 20 53 59 53 |OM DIGESTIVE SYS|
000010A0: 54 45 4D 20 49 4E 54 4F 20 42 4C 4F 4F 44 53 54 |TEM INTO BLOODST|
000010B0: 52 45 41 4D 2E 00 E7 14 38 04 8F 2D 4B 32 20 43 |REAM....8..-K2 C|
000010C0: 4F 4E 54 52 4F 4C 53 20 52 41 54 45 20 46 52 4F |ONTROLS RATE FRO|
000010D0: 4D 20 42 4C 4F 4F 44 53 54 52 45 41 4D 20 54 4F |M BLOODSTREAM TO|
000010E0: 20 55 52 49 4E 45 2E 00 ED 14 42 04 80 00 00 00 | URINE....B.....|
....... RATE 4.R.J.LAMB.1980.*....59468,
14.3....".".T.....8)"CONSECUTIVE REACTIO
NS.".U.....8)"......................"...
(.."...THIS PROGRAM WILL ALLOW YOU TO EX
AMINE".P.-.."THE EFFECT OF CHANGES IN TH
E RATE "...2.."CONSTANTS ON CONSECUTIVE
REACTIONS.".#.7.."..WE WILL BE CONCERNED
WITH THE ".B.<.."HYPOTHETICAL REACTION
:".`.A..".. A -> B -> C"...F..".
.WHERE A -> B HAS THE RATE CONSTANT K1,"
...K..".AND B -> C HAS THE RATE CONSTANT
K2."...P.."..PRESS ANY KEY TO CONTINUE.
"...U..A$:.A$."".85...Z..".":.130.+.C.."
.EXAMPLE OF COMPUTER DRAWN GRAPH..".[.D.
." 0 25 50 75 1
00"...E.." I-------I-------I------
-I------I"...F.." 0 ICB
A"...G.." 3 IC B
A "...H.." 6 IC
B A"...I.." 9 I C A B ".<
.J.." 12 I C A B".[.K.." 15
I A C B ".Y.L.." 18 I A
C B"...M.." 21 I A CB ".
..N.." 24 IA B C".U.O.." 27
IA B C"...P.." 30 IA
B C "...Q.." 33 IA B
C".@.R.." 36 IA B
C".F.S.." 39 IA B
C"...T.." 42 IA B
C"...U.." 45 IA B
C".Y.V.."..PRESS ANY KEY TO CONTINUE.
"...W..A$:.A$."".119...X........".DURING
A REACTION OF THIS SORT, THE ".I...."CO
NCENTRATION OF A DECREASES, THE ".W...."
CONCENTRATION OF B INCREASES AT FIRST ".
....."AND THEN DECREASES,AND THE CONCENT
RATION";.S...."OF C INCREASES DURING THE
REACTION."......"...THIS GIVES RISE TO
3 CURVES ON THE GRAPH".5. ..".AN EXAMPLE
OF THE COMPUTER DRAWN GRAPH".E...."AVAI
LABLE IN THIS PROGRAM IS SHOWN NEXT."...
...".IT SHOWS THE CHANGE IN CONCENTRATIO
N OF"......"A,B AND C AGAINST TIME..X...
."...PRESS ANY KEY TO CONTINUE."......A$
:.A$."".185......99.%.H..".THIS PROGRAM
WILL ALLOW YOU TO ALTER THE";.V.R.."VALU
ES OF THE RATE CONSTANTS,AND EXAMINE";..
...."THE RELATIVE CONCENTRATIONS OF A,B
AND C";......"AS THE REACTION PROGRESSES
."......"..THE SIMULATION HAS THE FOLLOW
ING LIMITATIONS :".-....".1. THE
RATE CONSTANTS MUST BE IN THE RANG
E 1 TO 0.001..\....".2. THE RATE CONSTAN
TS CANNOT BE EQUAL."......".3. THE REACT
ION CAN BE STUDIED FOR ANY TIME IN T
HE RANGE 15 TO 1000.".S...."....PRESS AN
Y KEY TO CONTINUE."..."..A$:.A$."".290..
...."."......"FIRST RATE CONSTANT = ";K1
.2....".SECOND RATE CONSTANT =";K2.M....
K1.K2.."..THE RATE CONSTANTS CANNOT BE E
QUAL...":.410......K1..1.K1...001.480...
B.."..RATE CONSTANT MUST BE IN THE RANGE
".G.L.."1 TO 0.001...".P.V..410......K2
..1.K2...001.500......450......"..WHAT I
S THE TIME PERIOD.";Z.-....Z..15.Z..1000
.530.\...."..MUST BE IN THE RANGE 15 TO
1000.":.500......"..WHAT TIME INCREMENT
DO YOU WANT"......".(MINIMUM INCREMENT
=";.(100.Z.15..5).100;")";.A.&..I...0..I
..(100.Z.15).100 .540...:.."."...D.."TIM
E."," %A"," %B"," %C".&.I.."....."," .
."," .."," .."./.N..".".<.X..T.0.Z.I.O.B
.A.100..(.K1.T).X.L.B.100.K1.(K2.K1).(.(
.K1.T)..(.K2.T))...V.C.100.(K2.K1).(K2.(
1..(.K1.T)).K1.(1..(.K2.T))).......(100.
T..5).100,.(100.A..5 ).100,.(100.B..5).1
00,.......(100.C..5).100............"..D
O YOU WANT A GRAPH?".0....A$:.A$."Y".710
.A....A$."N".1000.J....680.S.F.."."...P.
." 0 25 50 75 1
00"...Z.." I-------I-------I------
-I------I"......T.0.Z.I.R...A.100..(.K1.
T).....B.100.K1.(K2.K1).(.(.K1.T)..(.K2.
T))./...C.100.(K2.K1).(K2.(1..(.K1.T)).K
1.(1..(.K2.T))).>....T;.7)"I";.O....A.B.
B.C.850.`....A.C.C.B.900.Q. ..B.A.A.C.86
0...*..B.C.C.A .870...4..C.B.B.A.880...>
..C.A.A.B.890.P.R...C.3.5)"C";.B.3.5)"B"
;.A.3.5)"A":.910...\...C.3.5)"C";.A.3.5)
"A";.B.3.5)"B":.910.&.F...A.3.5)"A";.C.3
.5)"C";.B.3.5)"B":.910.Q.P...A.3.5)"A";.
B.3.5)"B";.C.3.5)"C":.910.|.Z...B.3.5)"B
";.A.3.5)"A";.C.3.5)"C":.910.......B.3.5
)"B";.C.3.5)"C";.A.3.5)"A":.910.........
....U...."..DO YOU WANT ANOTHER RUN?"...
...A$:.A$."Y".400......A$."N".1000......
930.-....".PLOT GRAPHS OF THE DATA YOU H
AVE ".P...."OBTAINED IN THIS SIMULATION.
......"...IN WHAT WAY ARE CONSECUTIVE RE
ACTIONS"......"RELEVANT IN OUR LIVES AND
WHY IS THIS SO?..."......-ANSWER-THE
ABSORPTION OF DRUGS/ALCOHOL INTO OUR BLO
ODSTREAM,AND THE.D....-AMOUNT OF TIME TH
EY ARE AT ACTIVE CONCENTRATIONS BEFORE B
EING.V.$..-DISCHARGED FROM OUR BODIES VI
A THE KIDNEYS.......-K1 CONTROLS RATE FR
OM DIGESTIVE SYSTEM INTO BLOODSTREAM....
8..-K2 CONTROLS RATE FROM BLOODSTREAM TO
URINE....B.....
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